Cancer is a leading underlying cause of death among people with learning disabilities, who are less likely to receive screening tests for the disease than those without learning disabilities. This article details a literature review that was undertaken to explore the experiences of general healthcare professionals in cancer assessment and treatment for people with learning disabilities. Two broad themes were identified: capacity and consent; and workforce and systemic factors. Issues were identified in relation to staff attitudes and values, resilience, training and education, ineffective systems for tracking populations who may require additional support, and improper application of capacity and consent legislation. Further research is required to develop and enhance services and staff experiences, to improve cancer outcomes for this patient population.